In yet another bold stride into healthcare, Amazon is setting its sights on transforming how patients access prescriptions. The company’s latest innovation — Amazon Pharmacy Kiosks — will begin rolling out in December 2025 across select One Medical offices in the Greater Los Angeles area. The move aims to close one of the most persistent gaps in patient care: the delay between a doctor’s appointment and getting medication in hand.
This initiative, while designed to simplify the patient experience, could have far-reaching implications for small businesses, local pharmacies, and healthcare providers navigating the fast-changing digital health landscape.
The Vision Behind Amazon’s Pharmacy Kiosks
Amazon’s entry into the pharmaceutical space has been years in the making. Since acquiring PillPack in 2018 and launching Amazon Pharmacy in 2020, the tech giant has steadily expanded its footprint in prescription fulfillment. The new kiosks mark a natural next step — one that blends Amazon’s trademark logistical efficiency with the clinical expertise of One Medical, the primary care provider it acquired in 2023.
The idea is simple yet powerful: remove friction from the prescription process.
According to Hannah McClellan, Vice President of Operations at Amazon Pharmacy, nearly one-third of all prescriptions in the U.S. go unfilled, often due to inconvenience or delay. “When patients have to make a separate stop after seeing their doctor, many prescriptions never get filled,” she noted. “By placing kiosks right at the point of care, we’re helping patients leave their appointment with medication in hand.”
This approach tackles a long-standing challenge in healthcare — medication adherence. For conditions that require immediate treatment, such as infections or acute pain, access delays can make the difference between a swift recovery and a complication.
How the Kiosks Work
The Amazon Pharmacy Kiosks will operate through a seamless digital workflow. Patients visiting a participating One Medical location can:
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Create or log into an Amazon Pharmacy account through the Amazon app.
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Schedule an appointment with their doctor and have prescriptions electronically sent to the kiosk.
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Select “Kiosk Pickup” at checkout.
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Scan a QR code generated by the app to collect their medication directly from the kiosk.
The process is designed to be as fast and intuitive as picking up an Amazon package. The company’s goal is to make pharmacy access instant, contactless, and friction-free.
Strategic Locations in Los Angeles
Amazon has chosen some of Los Angeles’ most densely populated and high-traffic areas for the pilot — including Downtown LA, Beverly Hills, and West Hollywood. These neighborhoods represent ideal test markets: they have a mix of urban professionals, tech-savvy consumers, and a strong base of One Medical patients.
For Amazon, Los Angeles offers both logistical convenience and brand visibility. For patients, it’s a chance to experience a more modern and efficient version of the pharmacy experience — one that aligns with today’s expectations for speed and simplicity.
A New Era of Patient Convenience
For decades, pharmacies have been an essential but often cumbersome part of healthcare. Long lines, insurance verification delays, and stock shortages have frustrated patients and strained providers. Amazon’s kiosk model seeks to turn that experience on its head.
Dr. Andrew Diamond, Chief Medical Officer at One Medical, underscored the clinical value of this system: “Knowing a patient can leave our office with their medication in hand—especially for conditions that require immediate attention—can make a meaningful difference in their care journey.”
The kiosks could also reduce the “treatment drop-off” problem. When patients postpone filling prescriptions, conditions can worsen, leading to higher medical costs later. By connecting prescription fulfillment directly to the point of care, Amazon hopes to close that gap — and position itself as a key player in the continuity of patient care.
What This Means for Small Business Pharmacies
While patients may applaud the convenience, independent pharmacies and small healthcare providers are watching the development closely — and with some concern.
Amazon’s entry adds pressure to an already competitive sector. Local pharmacies, which often operate on tight margins, could find it challenging to compete with Amazon’s combination of scale, pricing power, and technological integration.
1. Rising Expectations for Speed and Service
Patients who experience Amazon’s near-instant medication pickup will likely begin expecting similar convenience elsewhere. Independent pharmacies may need to modernize their systems, introducing features like mobile app ordering, same-day delivery, or automated prescription refills.
2. Technology Partnerships Become Essential
Rather than trying to compete head-on, small pharmacies might find opportunities in collaboration — such as partnering with telehealth providers, investing in prescription management software, or using third-party fulfillment networks. Innovation, rather than resistance, could be the key to survival.
3. The Loyalty Challenge
Amazon’s integration of healthcare services into its ecosystem — connecting pharmacy, telehealth, and delivery — creates a “sticky” customer experience. To counter this, small businesses may focus on personalized service, local expertise, and human relationships — qualities that large corporations often struggle to replicate.
The Bigger Picture: Amazon’s Growing Healthcare Ecosystem
Amazon’s latest move isn’t just about selling medication; it’s about building a comprehensive healthcare infrastructure.
The company’s portfolio now includes:
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One Medical – primary care clinics with in-person and virtual appointments.
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Amazon Clinic – a telehealth platform providing online consultations for minor conditions.
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Amazon Pharmacy – prescription fulfillment and home delivery.
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Amazon Pharmacy Kiosks – the new physical-digital hybrid point of care.
Together, these components form a vertically integrated ecosystem designed to keep patients within the Amazon loop — from diagnosis to treatment to medication. It’s a strategy reminiscent of how Amazon transformed retail logistics: control the entire customer journey, eliminate inefficiencies, and deliver a superior user experience.
For patients, that could mean unprecedented convenience. For competitors, it means keeping pace with a company that redefines industries every time it enters one.
Potential Challenges and Concerns
While the concept is promising, it’s not without challenges.
1. Regulatory and Compliance Issues
Pharmacy operations are heavily regulated, with stringent requirements around prescription handling, data privacy, and controlled substances. Amazon must navigate federal and state-level compliance frameworks, especially as it scales kiosk operations nationwide.
2. Data Security and Privacy
With healthcare data integrated into Amazon’s broader ecosystem, questions about data security and patient privacy are inevitable. Amazon’s vast data network could be both an asset and a liability if not handled transparently.
3. Impact on Local Economies
Small pharmacies and community-based healthcare providers often serve as neighborhood anchors. If Amazon’s model significantly disrupts their revenue streams, it could have unintended socioeconomic effects, especially in smaller or underserved areas.
4. Human Interaction in Healthcare
While convenience is valuable, the pharmacy experience often involves meaningful conversations — about dosage, side effects, and interactions. Replicating that human guidance through kiosks or apps remains a challenge, particularly for patients managing multiple medications or chronic conditions.
Opportunities Hidden in Disruption
Despite the challenges, Amazon’s innovation could inspire new opportunities across the healthcare ecosystem.
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For tech startups, there’s potential to develop software that integrates digital prescriptions, smart lockers, and pharmacy inventory systems.
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For local clinics, partnerships with tech-enabled pharmacies could streamline operations and reduce medication non-adherence rates.
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For traditional pharmacies, embracing automation and telepharmacy could open new service lines and improve operational efficiency.
Disruption, after all, often paves the way for reinvention.
The Future of Pharmacy: Hybrid, Tech-Driven, and Patient-Centered
Amazon’s pharmacy kiosks symbolize a broader shift in healthcare toward hybrid models — blending physical touchpoints with digital convenience. As consumers grow accustomed to instant services across industries, healthcare can no longer lag behind.
We’re moving toward a world where:
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Prescriptions are filled automatically,
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Refills are managed by AI,
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Kiosks and micro-clinics become standard in urban centers, and
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Patient care extends seamlessly from clinic to home.
For Amazon, this is not just about selling medicine — it’s about owning the healthcare experience. For small businesses, it’s a call to innovate, adapt, and redefine what personalized care means in a digital age.
Conclusion: Watching the Shift, Preparing for Change
The introduction of Amazon Pharmacy Kiosks may appear to be a convenience upgrade, but it’s much more than that. It represents a philosophical shift in healthcare delivery — one that prioritizes accessibility, technology, and speed.
As the kiosks debut across Los Angeles this December, the healthcare world will be watching closely. The benefits for patients are clear: faster access, fewer barriers, and improved adherence. Yet for small businesses, the ripple effects are just beginning.
Whether Amazon’s model becomes a nationwide standard or simply a catalyst for broader innovation, one thing is certain — the pharmacy of the future will look very different from the one we know today.

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